Hydrochloric Acid → HCID 21954458, compound

HRID 2305278Notes

Reaction equation

HRID 2305278 reaction equation
[C:1]([O:6][C:7]([C:10]12[CH2:19][C:14]3([O:20]COCCOC)[CH2:15][CH:16]([CH2:18][C:12]([O:27]COCCOC)([CH2:13]3)[CH2:11]1)[CH2:17]2)([CH3:9])[CH3:8])(=[O:5])[C:2]([CH3:4])=[CH2:3].Cl.[Cl-].[NH4+]>CC(C)=O>[OH:20][C:14]12[CH2:19][C:10]3([C:7]([O:6][C:1](=[O:5])[C:2]([CH3:4])=[CH2:3])([CH3:9])[CH3:8])[CH2:17][CH:16]([CH2:18][C:12]([OH:27])([CH2:11]3)[CH2:13]1)[CH2:15]2

Participants

5

Reactant 3

HCID 313Hydrochloric Acid2×HCID 25517Ammonium ChlorideHCID 23435157HCID 23435157, compound

Product 1

HCID 21954458HCID 21954458, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of 10 mmole of the above-prepared 1-(1-methacryloyloxy-1-methylethyl)-3,5-bis(2-methoxyethoxymethoxy)adamantane, 1 mmole (in terms of HCl) of 6 N-HCl, and 40 ml of acetone was stirred at room temperature for 5 hours. An aqueous ammonium chloride solution was added to the reaction mixture; the resulting mixture was extracted with ethyl acetate; the organic layer was concentrated; and the concentrate was subjected to column chromatography on a silica gel to yield the title compound.

Workup

  1. extractionthe resulting mixture was extracted with ethyl acetate
  2. concentrationthe organic layer was concentrated

Sources & evidence

ORD record
ord-9ca4312dd39741ca94dd5ec12ea88d0e
Source dataset
uspto-grants-2002_08
Patent number
US06440636B1

Reaction notes

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