Oxalyl chloride → HCID 10927507, compound

HRID 2305292Notes

Reaction equation

HRID 2305292 reaction equation
[Cl:1][C:2]1[C:3]([C:16]([CH:18]2[C:23](=[O:24])[CH2:22][CH2:21][CH2:20][C:19]2=O)=[O:17])=[CH:4][CH:5]=[C:6]2[C:11]=1[S:10](=[O:13])(=[O:12])[CH2:9][CH2:8][C:7]2([CH3:15])[CH3:14].C(Cl)(=O)C([Cl:29])=O>C(Cl)Cl.CN(C)C=O>[Cl:29][C:19]1[CH2:20][CH2:21][CH2:22][C:23](=[O:24])[C:18]=1[C:16]([C:3]1[C:2]([Cl:1])=[C:11]2[C:6]([C:7]([CH3:15])([CH3:14])[CH2:8][CH2:9][S:10]2(=[O:13])=[O:12])=[CH:5][CH:4]=1)=[O:17]

Participants

5

Reactant 2

HCID 65578Oxalyl chlorideHCID 11036363HCID 11036363, compound

Product 1

HCID 10927507HCID 10927507, compound

Reagents, catalysts & solvents 2

HCID 6228DimethylformamideCatalystHCID 6344DichloromethaneSolvent

Conditions

Temperature
25 °C

Procedure

2.0 g (5.2 mmol) of 2-(8-chloro-4,4-dimethyl-1,1-dioxothiochroman-7-yl)carbonyl-1,3-cyclohexanedione were dissolved in 30 ml of methylene chloride and 2.2 g (17.3 mmol) of oxalyl chloride and 2 drops of dimethylformamide were added. After 1 hour of stirring at 25° C., the solvent was removed. This gave 2.1 g of colored crystals.

Workup

  1. customthe solvent was removed

Sources & evidence

ORD record
ord-4465588775e045b5a484a24bcc9d2fbb
Source dataset
uspto-grants-2002_08
Patent number
US06440899B1

Reaction notes

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