Sodium Bicarbonate → HCID 18432837, compound

HRID 2305382Notes

Reaction equation

HRID 2305382 reaction equation
[N:1]([O-:3])=O.[Na+].[NH2:5][C:6]1[N:11]([CH2:12][C:13]2[CH:18]=[CH:17][N:16]=[CH:15][CH:14]=2)[C:10](=[O:19])[NH:9][C:8](=[O:20])[CH:7]=1.C(=O)(O)[O-].[Na+]>O.Cl>[NH2:5][C:6]1[N:11]([CH2:12][C:13]2[CH:14]=[CH:15][N:16]=[CH:17][CH:18]=2)[C:10](=[O:19])[NH:9][C:8](=[O:20])[C:7]=1[N:1]=[O:3]

Participants

6

Reactant 3

HCID 516892Sodium BicarbonateHCID 1526623HCID 1526623, compoundHCID 23668193Sodium Nitrite

Product 1

HCID 18432837HCID 18432837, compound

Reagents, catalysts & solvents 2

HCID 313Hydrochloric AcidSolventHCID 962WaterSolvent

Procedure

2.6 ml of 4N sodium nitrite was added to a solution of 2.35 g of 6-amino-1-(4-picolyl)-uracil in 25 ml of water and 4 ml of 5N HCl. After 15 minutes, 10 ml of 1N sodium bicarbonate was added. The solid was collected, washed and dried to give the title compound (2.15 g).

Workup

  1. customThe solid was collected
  2. washwashed
  3. customdried

Sources & evidence

ORD record
ord-9309492d914a4b22858fb9b2bbe60775
Source dataset
uspto-grants-2002_08
Patent number
US06440979B1

Reaction notes

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