Azide → HCID 22630141, compound

HRID 2307093Notes

Reaction equation

HRID 2307093 reaction equation
[N-]=[N+]=[N-].[ClH:4].[CH2:5]([C:8]1([NH2:18])[CH2:13][C:12]([CH3:15])([CH3:14])[CH2:11][C:10](C)([CH3:16])[CH2:9]1)C=C>>[ClH:4].[CH3:5][C:8]1([NH2:18])[CH2:13][C:12]([CH3:15])([CH3:14])[CH2:11][C:10]([CH3:16])=[CH:9]1

Participants

3

Reactant 2

HCID 33558AzideHCID 22630118HCID 22630118, compound

Product 1

HCID 22630141HCID 22630141, compoundYield 60%

Procedure

Prepared from azide 39 according to the procedure for compound 11 (Example 3, c). Amine hydrochloride 40 obtained as a colorless solid with 60% yield. 1H NMR (CDCl3, TMS): 0.96 and 1.07 (total 6H, both s, 5,5-CH3); 1.56 (3H, s, 1-CH3); 1.73 (3H, s, 3-CH3); 1.60-2.05 (4H, m, 4,6-CH2); 5.49 (1H, s, C═CH) and 8.27 ppm (3H, br s, NH3+).

Sources & evidence

ORD record
ord-43cd12063aa94d9f8bce29ac188d5e25
Source dataset
uspto-grants-2004_12
Patent number
US06828462B2

Reaction notes

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