1,2-Dichloro-3-ethynylbenzene → (Z)-2,3-dichlorostyryl-2-chloro-4-fluorobenzylsulfide

HRID 2308052Notes

Reaction equation

HRID 2308052 reaction equation
[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1[C:9]#[CH:10].[Cl:11][C:12]1[CH:19]=[C:18]([F:20])[CH:17]=[CH:16][C:13]=1[CH2:14][SH:15].[Na]>>[Cl:1][C:2]1[C:7]([Cl:8])=[CH:6][CH:5]=[CH:4][C:3]=1/[CH:9]=[CH:10]\[CH:14]([S:15][CH:14](/[CH:10]=[CH:9]\[C:3]1[CH:4]=[CH:5][CH:6]=[C:7]([Cl:8])[C:2]=1[Cl:1])[C:13]1[CH:16]=[CH:17][C:18]([F:20])=[CH:19][C:12]=1[Cl:11])[C:13]1[CH:16]=[CH:17][C:18]([F:20])=[CH:19][C:12]=1[Cl:11]

Participants

4

Reactant 3

HCID 1787791,2-Dichloro-3-ethynylbenzeneHCID 5360545SodiumHCID 22026132(2-chloro-4-fluorophenyl)methanethiol

Product 1

HCID 86593391(Z)-2,3-dichlorostyryl-2-chloro-4-fluorobenzylsulfide

Procedure

A solution of 2,3-dichlorophenylacetylene (0.02 mol), 2-chloro-4-fluorobenzyl mercaptan (0.02 mol) and metallic sodium (0.02 g atom) is subjected to the General Procedure to form (Z)-2,3-dichlorostyryl-2-chloro-4-fluorobenzylsulfide. The title compound is obtained following oxidation of the sulfide, according to the General Procedure.

Sources & evidence

ORD record
ord-ce50bb29e50f4b6aa7f30ff89fdfd925
Source dataset
uspto-grants-2004_12
Patent number
US06833480B2

Reaction notes

Loading…