HCID 9814764, compound → HCID 9878521, compound

HRID 2308180Notes

Reaction equation

HRID 2308180 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][CH:7]=[C:8]2[C:13]=1[N:12]=[CH:11][C:10]([N:14]1[CH:20]3[CH2:21][CH2:22][N:17]([CH2:18][CH2:19]3)[CH2:16][CH2:15]1)=[CH:9]2)([O-])=O>O.C(O)(=O)C.[Fe]>[NH2:1][C:4]1[CH:5]=[CH:6][CH:7]=[C:8]2[C:13]=1[N:12]=[CH:11][C:10]([N:14]1[CH:20]3[CH2:19][CH2:18][N:17]([CH2:22][CH2:21]3)[CH2:16][CH2:15]1)=[CH:9]2

Participants

5

Reactant 1

HCID 9814764HCID 9814764, compound

Product 1

HCID 9878521HCID 9878521, compound

Reagents, catalysts & solvents 3

HCID 23925IronCatalystHCID 176Acetic AcidSolventHCID 962WaterSolvent

Conditions

Temperature
40 °C

Procedure

0.8 g (2.7 mmol) of 4-(8-nitroquinolin-3-yl)-1,4-diazabicyclo[3.2.2]nonane, in suspension in a mixture of 8 ml of water and 4 ml of acetic acid, is introduced into a 25 ml three-necked round-bottomed flask and the suspension is heated at 40° C.; 0.43 g (7.7 mmol) of iron are then added, in two portions, and the mixture is heated at 50° C. for 1 h.

Workup

  1. additionis introduced into a 25 ml three-necked round-bottomed flask
  2. temperaturethe mixture is heated at 50° C. for 1 h.

Sources & evidence

ORD record
ord-48220eb7fd9849859499fbfcd2537a22
Source dataset
uspto-grants-2004_12
Patent number
US06835730B2

Reaction notes

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