Triethylamine → HCID 18381305, compound

HRID 2308818Notes

Reaction equation

HRID 2308818 reaction equation
Cl.CS([S:7][CH2:8][CH2:9][NH2:10])=C(O)O.[C:11]([NH:14][CH2:15][CH2:16][SH:17])(=[O:13])[CH3:12].C(N(CC)CC)C>CO>[NH2:10][CH2:9][CH2:8][S:7][S:17][CH2:16][CH2:15][NH:14][C:11](=[O:13])[CH3:12]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 14484AcetylcysteamineHCID 88629399HCID 88629399, compound

Product 1

HCID 18381305HCID 18381305, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The method of S. J. Brois et al. (loc. cit.) was employed. Methyl-2-aminoethylsulfenylthiocarbonate hydrochloride in methanol solution was treated with acetylcysteamine at 0° C. The reaction, without triethylamine accelerator, was practically instantaneous.

Workup

  1. customThe reaction

Sources & evidence

ORD record
ord-5592d050e2b24d25b448c5f302bd73ff
Source dataset
uspto-grants-1987_09
Patent number
US04691023

Reaction notes

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