Ethanolamine → 2-n-Butyl-2-oxazoline

HRID 2309307Notes

Reaction equation

HRID 2309307 reaction equation
[C:1](#[N:6])[CH2:2][CH2:3][CH2:4][CH3:5].[CH2:7]([CH2:9]N)[OH:8]>O.O.C([O-])(=O)C.[Cd+2].C([O-])(=O)C>[CH2:2]([C:1]1[O:8][CH2:7][CH2:9][N:6]=1)[CH2:3][CH2:4][CH3:5]

Participants

4

Reactant 2

HCID 700EthanolamineHCID 8061Valeronitrile

Product 1

HCID 122096302-n-Butyl-2-oxazoline

Reagents, catalysts & solvents 1

HCID 6537495Cadmium acetate, dihydrateCatalyst

Conditions

Temperature
124 °C

Procedure

A mixture of about 83.1 grams (1.00 mole) valeronitrile, about 64.8 grams (1.05 mole) ethanolamine, and about 6.2 grams (0.025 mole) cadmium acetate dihydrate is heated at about 124 degrees C. to about 128 degrees C. and stirred under nitrogen for about two days. The product is then distilled under vacuum. The fraction boiling at about 67 degrees C. to about 75.5 degrees C. at about 28 mmHg is collected.

Workup

  1. customto about 128 degrees C
  2. distillationThe product is then distilled under vacuum
  3. customto about 75.5 degrees C
  4. customat about 28 mmHg is collected

Sources & evidence

ORD record
ord-68da6a0672f442fda88c211acb5feef7
Source dataset
uspto-grants-1987_09
Patent number
US04695295

Reaction notes

Loading…