2-Phenylacetophenone → HCID 20067692, compound

HRID 2309776Notes

Reaction equation

HRID 2309776 reaction equation
[C:1]1([C:7]([CH2:9][C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[CH2:16]([O:18][CH:19]([O:22][CH2:23][CH3:24])[CH2:20]Br)[CH3:17]>CCCC[N+](CCCC)(CCCC)CCCC.[OH-].CC[N+](CC1C=CC=CC=1)(CC)CC.[Cl-]>[CH2:16]([O:18][CH:19]([O:22][CH2:23][CH3:24])[CH2:20][CH:9]([C:10]1[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=1)[C:7]([C:1]1[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1)=[O:8])[CH3:17]

Participants

5

Reactant 2

HCID 99482-PhenylacetophenoneHCID 74852Ethane, 2-bromo-1,1-diethoxy-

Product 1

HCID 20067692HCID 20067692, compound

Reagents, catalysts & solvents 2

HCID 66133Benzyl triethylammonium chlorideCatalystHCID 2723671Tetrabutylammonium HydroxideCatalyst

Procedure

The compound is prepared from 19.6 g of desoxybenzoin and 19.7 g of bromacetaldehyde diethyl acetal according to the procedure in Example 1(a). The reaction is performed however at 90° C. and using TBAH as catalyst instead of TEBAC.

Workup

  1. customis performed however at 90° C.

Sources & evidence

ORD record
ord-133673c31e0647b0ae79a9488db7d975
Source dataset
uspto-grants-1987_09
Patent number
US04696949

Reaction notes

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