Hydrogen Bromide → HCID 13809062, compound

HRID 2309852Notes

Reaction equation

HRID 2309852 reaction equation
[CH3:1][O:2][C:3]([C@H:5]1[C@H:9]([C:10]([O:12][CH3:13])=[O:11])[O:8][C:7]([CH2:24][CH3:25])([C:14]2[CH:19]=[CH:18][C:17]([CH2:20][CH:21]([CH3:23])[CH3:22])=[CH:16][CH:15]=2)[O:6]1)=[O:4].[BrH:26].BrBr>ClCCCl>[CH3:1][O:2][C:3]([C@H:5]1[C@H:9]([C:10]([O:12][CH3:13])=[O:11])[O:8][C:7]([CH:24]([Br:26])[CH3:25])([C:14]2[CH:15]=[CH:16][C:17]([CH2:20][CH:21]([CH3:22])[CH3:23])=[CH:18][CH:19]=2)[O:6]1)=[O:4]

Participants

5

Reactant 3

HCID 260Hydrogen BromideHCID 24408BromineHCID 13809050HCID 13809050, compound

Product 1

HCID 13809062HCID 13809062, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent2×

Procedure

To a solution in 1,2-dichloroethane (70 ml) of 2-ethyl-2-[4-(2-methylpropyl)-phenyl]-1,3-dioxolane-4(R),5(R)-dicarboxylic acid dimethylester (7.0 g; 20 mmoles obtained according to ex. 29), deoxygenated and added with hydrobromic acid (0.324 g; 4 mmoles), it is added dropwise in 1 h under inert atmosphere at +15° C., a solution of bromine (3.20 g; 20 mmoles) in 1,2-dichloroethane (7.0 ml) previously deoxygenated.

Workup

  1. additionis added dropwise in 1 h under inert atmosphere at +15° C.

Sources & evidence

ORD record
ord-bbba3449bca24b7e865c5c0247e0d317
Source dataset
uspto-grants-1987_09
Patent number
US04697036

Reaction notes

Loading…