Water → 1-Benzyl-4-phenyl-3-pyrrolidinemethanol

HRID 2310394Notes

Reaction equation

[Al+3:34].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([C:19](=[O:20])[N:21]2[CH:22]([c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:29][O:30][C:31]2=[O:32])[CH:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:12]1.[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[H-:33].[H-:36].[H-:37].[H-:38].[Li+:35].[OH2:39]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH2:19][OH:20])[CH:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:12]1

Participants

Reactant 6

HCID 962Water

HCID 8028Tetrahydrofuran

HCID 28486Lithium ion

HCID 104727Aluminum Cation

HCID 166653Hydride4×

HCID 229124353-(1-Benzyl-4-phenylpyrrolidine-3-carbonyl)-4-phenyl-1,3-oxazolidin-2-one

Product 1

HCID 219127561-Benzyl-4-phenyl-3-pyrrolidinemethanol

Sources & evidence

ORD record: ord-0d91f28bf8ed4fb9a5594ba942df6272
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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