Dimethylformamide → 7-[2-(4-acetylpiperazin-1-yl)ethoxy]-4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinazoline
Reaction equation
[Br:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([O:27][CH3:28])[cH:7][c:8]2[c:9]([O:15][c:16]3[c:17]([F:26])[c:18]4[cH:19][c:20]([CH3:25])[nH:21][c:22]4[cH:23][cH:24]3)[n:10][cH:11][n:12][c:13]2[cH:14]1.[C:49]([CH3:50])(=[O:51])[N:52]1[CH2:53][CH2:54][NH:55][CH2:56][CH2:57]1.[CH3:58][N:59]([CH3:60])[CH:61]=[O:62].[c:29]1([P:30](=[O:31])([c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:38]2[cH:39][cH:40][cH:41][cH:42][cH:43]2)[cH:44][cH:45][cH:46][cH:47][cH:48]1>>[CH2:2]([CH2:3][O:4][c:5]1[c:6]([O:27][CH3:28])[cH:7][c:8]2[c:9]([O:15][c:16]3[c:17]([F:26])[c:18]4[cH:19][c:20]([CH3:25])[nH:21][c:22]4[cH:23][cH:24]3)[n:10][cH:11][n:12][c:13]2[cH:14]1)[N:55]1[CH2:54][CH2:53][N:52]([C:49]([CH3:50])=[O:51])[CH2:57][CH2:56]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-22aa05daf5344c88a1a2ec698d2104cf
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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