Potassium Cation → 4-chloro-3-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-N-[2-(3-hydroxy-2,2-dimethyl-propoxy)-phenyl]-N-methyl-benzamide

HRID 2310685Notes

Reaction equation

HRID 2310685 reaction equation
[Br:31][CH2:32][C:33]([CH2:34][OH:35])([CH3:36])[CH3:37].[CH3:49][CH2:50][O:51][C:52]([CH3:53])=[O:54].[Cl:1][c:2]1[c:3](-[c:19]2[cH:20][n:21][c:22]([C:27]([F:28])([F:29])[F:30])[cH:23][c:24]2[C:25]#[N:26])[cH:4][c:5]([C:6](=[O:7])[N:8]([CH3:9])[c:10]2[c:11]([OH:16])[cH:12][cH:13][cH:14][cH:15]2)[cH:17][cH:18]1.[K+:38].[K+:39].[O-:40][C:41]([O-:42])=[O:43].[O:44]=[CH:45][N:46]([CH3:47])[CH3:48]>>[Cl:1][c:2]1[c:3](-[c:19]2[cH:20][n:21][c:22]([C:27]([F:28])([F:29])[F:30])[cH:23][c:24]2[C:25]#[N:26])[cH:4][c:5]([C:6](=[O:7])[N:8]([CH3:9])[c:10]2[c:11]([O:16][CH2:32][C:33]([CH2:34][OH:35])([CH3:36])[CH3:37])[cH:12][cH:13][cH:14][cH:15]2)[cH:17][cH:18]1

Participants

7

Reactant 6

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 1425013-Bromo-2,2-dimethyl-1-propanolHCID 686028394-chloro-3-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-N-(2-hydroxy-phenyl)-N-methyl-benzamide

Product 1

HCID 686025284-chloro-3-(4-cyano-6-trifluoromethyl-pyridin-3-yl)-N-[2-(3-hydroxy-2,2-dimethyl-propoxy)-phenyl]-N-methyl-benzamide

Sources & evidence

ORD record
ord-f5cca29ee3d04ab399a7a6c321c3dea5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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