p-Toluenesulfonic acid → tert-Butyl 4-(pyrrolidin-1-yl)-3,6-dihydropyridine-1(2H)-carboxylate

HRID 2311352Notes

Reaction equation

HRID 2311352 reaction equation
[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][C:11](=[O:14])[CH2:12][CH2:13]1.[CH2:15]1[CH2:16][CH2:17][NH:18][CH2:19]1.[CH2:31]1[CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]1.[CH3:20][c:21]1[cH:22][cH:23][c:24]([S:25]([OH:26])(=[O:27])=[O:28])[cH:29][cH:30]1>>[C:1](=[O:2])([O:3][C:4]([CH3:5])([CH3:6])[CH3:7])[N:8]1[CH2:9][CH2:10][C:11]([N:18]2[CH2:17][CH2:16][CH2:15][CH2:19]2)=[CH:12][CH2:13]1

Participants

5

Reactant 4

HCID 6101p-Toluenesulfonic acidHCID 8078CyclohexaneHCID 31268PyrrolidineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

Product 1

HCID 1514431tert-Butyl 4-(pyrrolidin-1-yl)-3,6-dihydropyridine-1(2H)-carboxylate

Sources & evidence

ORD record
ord-757809471df14e879e53a662a1c922ef
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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