Tetrahydrofuran → 2-[2-(4-Chloro-5-fluoro-3-methyl-2-pyridinyl)cyclopropyl]ethanol
Reaction equation
[Al+3:20].[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[Cl:1][c:2]1[c:3]([CH3:18])[c:4]([CH:9]2[CH:10]([CH2:12][C:13](=[O:14])[O:15][CH2:16][CH3:17])[CH2:11]2)[n:5][cH:6][c:7]1[F:8].[H-:19].[H-:22].[H-:23].[H-:24].[Li+:21]>>[Cl:1][c:2]1[c:3]([CH3:18])[c:4]([CH:9]2[CH:10]([CH2:12][CH2:13][OH:14])[CH2:11]2)[n:5][cH:6][c:7]1[F:8]Participants
6
Sources & evidence
- ORD record
- ord-2ba0b845bd604d8c8052fac5a984d104
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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