Chloroform → N-[1-[[2-hydroxy-1-[(2-hydroxycyclohexyl)amino]-1-oxoheptan-3-yl]carbamoyl]cyclohexyl]morpholine-4-carboxamide

HRID 2311734Notes

Reaction equation

HRID 2311734 reaction equation
[C:26]([Cl:27])(=[O:28])[C:29]([CH3:30])([CH3:31])[CH3:32].[CH3:19][CH2:20][N:21]([CH2:22][CH3:23])[CH2:24][CH3:25].[CH:51]([Cl:52])([Cl:53])[Cl:54].[O:1]1[CH2:2][CH2:3][N:4]([C:7](=[O:8])[NH:9][C:10]2([C:16](=[O:17])[OH:18])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)[CH2:5][CH2:6]1.[O:55]1[CH2:56][CH2:57][CH2:58][CH2:59]1.[OH:33][CH:34]1[CH:35]([NH:40][C:41]([CH:42]([CH:43]([CH2:44][CH2:45][CH2:46][CH3:47])[NH2:48])[OH:49])=[O:50])[CH2:36][CH2:37][CH2:38][CH2:39]1>>[O:1]1[CH2:2][CH2:3][N:4]([C:7](=[O:8])[NH:9][C:10]2([C:16](=[O:18])[NH:48][CH:43]([CH:42]([C:41]([NH:40][CH:35]3[CH:34]([OH:33])[CH2:39][CH2:38][CH2:37][CH2:36]3)=[O:50])[OH:49])[CH2:44][CH2:45][CH2:46][CH3:47])[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2)[CH2:5][CH2:6]1

Participants

7

Reactant 6

HCID 6212ChloroformHCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 62493Pivaloyl chlorideHCID 115071371-(Morpholine-4-carboxamido)cyclohexanecarboxylic acidHCID 178510223-amino-2-hydroxy-N-(2-hydroxycyclohexyl)heptanamide

Product 1

HCID 85075519N-[1-[[2-hydroxy-1-[(2-hydroxycyclohexyl)amino]-1-oxoheptan-3-yl]carbamoyl]cyclohexyl]morpholine-4-carboxamide

Sources & evidence

ORD record
ord-f6aad75e25a14e729b59875255c10de0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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