Methanol → 6-{3-Chloro-4-[3,3,3-trifluoro-2-hydroxy-1-methyl-2-(2-methyl-pyridin-4-yl)-propyl]-phenyl}-nicotinic acid
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:1][O:2][C:3]([c:4]1[cH:5][n:6][c:7](-[c:10]2[cH:11][c:12]([Cl:31])[c:13]([CH:16]([C:17]([C:18]([F:19])([F:20])[F:21])([c:22]3[cH:23][c:24]([CH3:28])[n:25][cH:26][cH:27]3)[OH:29])[CH3:30])[cH:14][cH:15]2)[cH:8][cH:9]1)=[O:32].[CH3:35][OH:36].[Li+:34].[OH-:33]>>[O:2]=[C:3]([c:4]1[cH:5][n:6][c:7](-[c:10]2[cH:11][c:12]([Cl:31])[c:13]([CH:16]([C:17]([C:18]([F:19])([F:20])[F:21])([c:22]3[cH:23][c:24]([CH3:28])[n:25][cH:26][cH:27]3)[OH:29])[CH3:30])[cH:14][cH:15]2)[cH:8][cH:9]1)[OH:32]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1b4b4ac0a4b1451e9904ac41e172572b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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