Potassium Cation → Tert-butyl 2-[1-[[2-chloro-6-(difluoromethyl)phenyl]methyl]-3-[(1-hexylpiperidin-4-yl)carbamoyl]-4-methylpyrrolidin-3-yl]acetate
Reaction equation
[Br:6][CH2:7][c:8]1[c:9]([Cl:17])[cH:10][cH:11][cH:12][c:13]1[CH:14]([F:15])[F:16].[C:18](=[O:19])([O-:20])[O-:21].[CH2:24]([CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[N:30]1[CH2:31][CH2:32][CH:33]([NH:36][C:37](=[O:38])[C:39]2([CH2:45][C:46](=[O:47])[O:48][C:49]([CH3:50])([CH3:51])[CH3:52])[CH2:40][NH:41][CH2:42][CH:43]2[CH3:44])[CH2:34][CH2:35]1.[CH3:1][N:2]([CH3:3])[CH:4]=[O:5].[CH3:54][CH2:55][O:56][C:57](=[O:58])[CH3:59].[K+:22].[K+:23].[OH2:53]>>[CH2:7]([c:8]1[c:9]([Cl:17])[cH:10][cH:11][cH:12][c:13]1[CH:14]([F:15])[F:16])[N:41]1[CH2:40][C:39]([C:37]([NH:36][CH:33]2[CH2:32][CH2:31][N:30]([CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH3:29])[CH2:35][CH2:34]2)=[O:38])([CH2:45][C:46](=[O:47])[O:48][C:49]([CH3:50])([CH3:51])[CH3:52])[CH:43]([CH3:44])[CH2:42]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-c3dc3bd37bf34fd69e4291fa40512550
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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