Ethyl Acetate → HCID 20034840, compound

HRID 231278Notes

Reaction equation

HRID 231278 reaction equation
C(OCC)(=O)C.[CH3:7][O:8][CH:9]([CH2:18][O:19][CH2:20][CH2:21][CH:22]([CH3:39])[CH2:23][CH2:24][CH2:25][CH:26]([CH3:38])[CH2:27][CH2:28][CH2:29][CH:30]([CH3:37])[CH2:31][CH2:32][CH2:33][CH:34]([CH3:36])[CH3:35])[CH2:10][S:11]([CH2:14][CH2:15][CH2:16][OH:17])(=[O:13])=[O:12].[CH3:40][S:41](Cl)(=[O:43])=[O:42]>C(N(CC)CC)C>[CH3:7][O:8][CH:9]([CH2:18][O:19][CH2:20][CH2:21][CH:22]([CH3:39])[CH2:23][CH2:24][CH2:25][CH:26]([CH3:38])[CH2:27][CH2:28][CH2:29][CH:30]([CH3:37])[CH2:31][CH2:32][CH2:33][CH:34]([CH3:36])[CH3:35])[CH2:10][S:11]([CH2:14][CH2:15][CH2:16][O:17][S:41]([CH3:40])(=[O:43])=[O:42])(=[O:13])=[O:12]

Participants

5

Reactant 3

HCID 8857Ethyl AcetateHCID 31297Methanesulfonyl chlorideHCID 20034835HCID 20034835, compound

Product 1

HCID 20034840HCID 20034840, compound

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

To 100 ml of ethyl acetate are added 4.5 g of 3-[(2-methoxy-3-(3,7,11,15-tetramethylhexadecyloxy)propyl)sulfonyl]propanol and 1.54 ml of triethylamine, to which is further added 0.85 ml of methanesulfonyl chloride dropwise at room temperature with stirring. After being stirred at room temperature for 3 hours, the reaction mixture is washed with water, dilute hydrochloric acid, an aquoues sodium bicarbonate and water. After drying, the solvent is distilled off to leave 5.16 g of the captioned compound as an oily substance.

Workup

  1. customdropwise at room temperature
  2. stirringAfter being stirred at room temperature for 3 hours
  3. washthe reaction mixture is washed with water, dilute hydrochloric acid
  4. customAfter drying
  5. distillationthe solvent is distilled off

Sources & evidence

ORD record
ord-982afbba8e6b428d87093010c49ef90d
Source dataset
uspto-grants-1989_07
Patent number
US04845219

Reaction notes

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