Tetrahydrofuran → 4-chloro-5-iodo-7-(1,4-dioxaspiro[4.5]decan-8-yl)-7H-pyrrolo[2,3-d]pyrimidine
Reaction equation
[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[nH:8][cH:9][c:10]2[I:11].[O:12]1[CH2:13][CH2:14][O:15][C:16]12[CH2:17][CH2:18][CH:19]([OH:22])[CH2:20][CH2:21]2.[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[Cl:1][c:2]1[c:3]2[c:4]([n:5][cH:6][n:7]1)[n:8]([CH:19]1[CH2:18][CH2:17][C:16]3([O:12][CH2:13][CH2:14][O:15]3)[CH2:21][CH2:20]1)[cH:9][c:10]2[I:11]Participants
5
Sources & evidence
- ORD record
- ord-c797a5c1ac104747bddcb73514ee281d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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