Ammonium → Tert-butyl 3-[benzyl(1-phenylethyl)amino]-2-hydroxy-3-phenylpropanoate

HRID 2313458Notes

Reaction equation

HRID 2313458 reaction equation
[C:22]([CH3:23])([CH3:24])([CH3:25])[O:26][C:27]([CH:28]=[CH:29][c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1)=[O:36].[CH2:17]([Li:18])[CH2:19][CH2:20][CH3:21].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[NH:8][CH:9]([CH3:10])[c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1.[CH3:44][CH2:45][CH2:46][CH2:47][CH2:48][CH3:49].[Cl-:37].[NH4+:38].[O:39]1[CH2:40][CH2:41][CH2:42][CH2:43]1>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]([CH:9]([CH3:10])[c:11]1[cH:12][cH:13][cH:14][cH:15][cH:16]1)[CH:29]([CH:28]([C:27]([O:26][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:36])[OH:39])[c:30]1[cH:31][cH:32][cH:33][cH:34][cH:35]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 312ChlorideHCID 8028TetrahydrofuranHCID 8058HexaneHCID 347555Tert-butyl cinnamateHCID 519427N-benzyl-1-phenylethylamineHCID 178418339Butyllithium

Product 1

HCID 15226470Tert-butyl 3-[benzyl(1-phenylethyl)amino]-2-hydroxy-3-phenylpropanoate

Sources & evidence

ORD record
ord-e58a2a1ac45b429da056afca46bc7421
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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