反应详情

A mixture of tetrahydrothiopyran-3-one-1,1-dioxide (0.830 g, 0.0056 moles), 3-nitrobenzaldehyde (0.846 g, 0.0056 moles) and methyl 3-aminocrotonate (0.644 g, 0.0056 moles) in methanol (20 mL) was refluxed for 16 hours. After cooling, the resulting solid was isolated by filtration and washed with diethyl ether. This solid was dried at 40° C. for 4 hours under vacuum to give 0.620 g product; mp 236°-238° C.

1. temperaturewas refluxed for 16 hours
2. temperatureAfter cooling
3. customthe resulting solid was isolated by filtration
4. washwashed with diethyl ether
5. customThis solid was dried at 40° C. for 4 hours under vacuum