Acetic Acid → 4-(Benzo[b]thiophen-2-yl)-5-bromo-2-chloropyrimidine
Reaction equation
[Br:15][c:16]1[cH:17][n:18][c:19]([Cl:22])[n:20][cH:21]1.[CH2:1]([Li:2])[CH2:3][CH2:4][CH3:5].[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:23][C:24](=[O:25])[OH:26].[CH:46]([Cl:47])([Cl:48])[Cl:49].[Cl:27][C:28]1=[C:39]([Cl:40])[C:37](=[O:38])[C:34]([C:35]#[N:36])=[C:31]([C:32]#[N:33])[C:29]1=[O:30].[Cl:50][CH2:51][Cl:52].[s:6]1[c:7]2[c:8]([cH:9][cH:10]1)[cH:11][cH:12][cH:13][cH:14]2>>[s:6]1[c:7]2[c:8]([cH:9][c:10]1-[c:17]1[c:16]([Br:15])[cH:21][n:20][c:19]([Cl:22])[n:18]1)[cH:11][cH:12][cH:13][cH:14]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-385e6536e458464f83b6523cf20ed6fc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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