Tetrahydrofuran → Methyl 2-(4-bromo-2-fluorophenylamino)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]([F:9])[c:5]([NH2:8])[cH:6][cH:7]1.[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:10][Si:11]([N-:12][Si:13]([CH3:14])([CH3:15])[CH3:16])([CH3:17])[CH3:18].[CH3:20][O:21][C:22](=[O:23])[c:24]1[c:25]([Cl:32])[n:26]([CH3:31])[c:27](=[O:30])[cH:28][cH:29]1.[Li+:19]>>[Br:1][c:2]1[cH:3][c:4]([F:9])[c:5]([NH:8][c:25]2[c:24]([C:22]([O:21][CH3:20])=[O:23])[cH:29][cH:28][c:27](=[O:30])[n:26]2[CH3:31])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-a5ae4018f1d6404ebaa8b16a0533eef7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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