Hydroxide → 2,4-Diamino-6-ethyl-5-(3-(7-fluoro-2-methylquinolin-4-yloxy)propoxy)pyrimidine
Reaction equation
[F:15][c:16]1[cH:17][cH:18][c:19]2[c:20]([O:27][CH2:28][CH2:29][CH2:30][Br:31])[cH:21][c:22]([CH3:26])[n:23][c:24]2[cH:25]1.[Li+:14].[NH2:1][c:2]1[n:3][c:4]([CH2:10][CH3:11])[c:5]([OH:9])[c:6]([NH2:8])[n:7]1.[O:32]=[CH:33][N:34]([CH3:35])[CH3:36].[OH-:13].[OH2:12]>>[NH2:1][c:2]1[n:3][c:4]([CH2:10][CH3:11])[c:5]([O:9][CH2:30][CH2:29][CH2:28][O:27][c:20]2[c:19]3[cH:18][cH:17][c:16]([F:15])[cH:25][c:24]3[n:23][c:22]([CH3:26])[cH:21]2)[c:6]([NH2:8])[n:7]1Participants
7
Sources & evidence
- ORD record
- ord-eb22fe366ed7453ea41f8a734e99514c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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