Triphenylphosphine → (6-{2-[2-(4-Trifluoromethyl-phenyl)-thiazol-4-yl]-ethoxy]-indol-1-yl)-acetic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][cH:10][c:11]2[cH:12][cH:13][c:14]([OH:17])[cH:15][c:16]12)=[O:18].[F:19][C:20]([c:21]1[cH:22][cH:23][c:24](-[c:27]2[s:28][cH:29][c:30]([CH2:32][CH2:33][OH:34])[n:31]2)[cH:25][cH:26]1)([F:35])[F:36].[N:56]([C:57]([O:58][C:59]([CH3:60])([CH3:61])[CH3:62])=[O:63])=[N:64][C:65]([O:66][C:67]([CH3:68])([CH3:69])[CH3:70])=[O:71].[c:37]1([P:38]([c:39]2[cH:40][cH:41][cH:42][cH:43][cH:44]2)[c:45]2[cH:46][cH:47][cH:48][cH:49][cH:50]2)[cH:51][cH:52][cH:53][cH:54][cH:55]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH2:7][n:8]1[cH:9][cH:10][c:11]2[cH:12][cH:13][c:14]([O:17][CH2:33][CH2:32][c:30]3[cH:29][s:28][c:27](-[c:24]4[cH:23][cH:22][c:21]([C:20]([F:19])([F:35])[F:36])[cH:26][cH:25]4)[n:31]3)[cH:15][c:16]12)=[O:18]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-690bbb57bf144bef828678bed9027a12
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…