Tetrahydrofuran → 3-{2-[4-(4-Chloro-3-methoxy-phenyl)-piperazin-1-yl]-2-oxo-ethyl}-6-[2-(tetrahydro-pyran-2-yloxy)-ethoxy]-3H-benzooxazol-2-one
Reaction equation
[CH2:71]1[O:72][CH2:73][CH2:74][CH2:75]1.[Cl:32][c:33]1[c:34]([O:59][CH3:60])[cH:35][c:36]([N:39]2[CH2:40][CH2:41][N:42]([C:45]([CH2:46][n:47]3[c:48](=[O:57])[o:49][c:50]4[c:51]3[cH:52][cH:53][c:54]([OH:56])[cH:55]4)=[O:58])[CH2:43][CH2:44]2)[cH:37][cH:38]1.[O:20]=[C:21]([O:22][CH2:23][CH3:24])[N:25]=[N:26][C:27]([O:28][CH2:29][CH3:30])=[O:31].[O:61]1[CH:62]([O:67][CH2:68][CH2:69][OH:70])[CH2:63][CH2:64][CH2:65][CH2:66]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[Cl:32][c:33]1[c:34]([O:59][CH3:60])[cH:35][c:36]([N:39]2[CH2:40][CH2:41][N:42]([C:45]([CH2:46][n:47]3[c:48](=[O:57])[o:49][c:50]4[c:51]3[cH:52][cH:53][c:54]([O:56][CH2:69][CH2:68][O:67][CH:62]3[O:61][CH2:66][CH2:65][CH2:64][CH2:63]3)[cH:55]4)=[O:58])[CH2:43][CH2:44]2)[cH:37][cH:38]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-1602f2c475554d14b612cf9ac276bc33
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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