Dimethylformamide → 2-fluoro-3-(3-{[1-(2-fluoroethyl)-1H-pyrazol-4-yl]ethynyl}phenyl)pyridine
Reaction equation
[C:10](#[CH:11])[c:12]1[cH:13][c:14](-[c:18]2[c:19]([F:24])[n:20][cH:21][cH:22][cH:23]2)[cH:15][cH:16][cH:17]1.[Cu:30]([I:31])[I:32].[F:1][CH2:2][CH2:3][n:4]1[n:5][cH:6][c:7]([I:9])[cH:8]1.[O:25]=[CH:26][N:27]([CH3:28])[CH3:29]>>[F:1][CH2:2][CH2:3][n:4]1[n:5][cH:6][c:7]([C:11]#[C:10][c:12]2[cH:13][c:14](-[c:18]3[c:19]([F:24])[n:20][cH:21][cH:22][cH:23]3)[cH:15][cH:16][cH:17]2)[cH:8]1Participants
5
Sources & evidence
- ORD record
- ord-54b836b4485c4226ac862f6b25b929e2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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