Dimethylformamide → 2-[2-Bromo-5-(tert-butyl-dimethyl-silanyloxy)-benzyl]-isoindole-1,3-dione

HRID 2315161Notes

Reaction equation

HRID 2315161 reaction equation
[Br:1][c:2]1[c:3]([CH2:16][Br:17])[cH:4][c:5]([O:6][Si:7]([CH3:8])([CH3:9])[C:10]([CH3:11])([CH3:12])[CH3:13])[cH:14][cH:15]1.[C:18]1(=[O:28])[c:19]2[c:20]([cH:24][cH:25][cH:26][cH:27]2)[C:21](=[O:23])[NH:22]1.[K:29].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[Br:1][c:2]1[c:3]([CH2:16][N:22]2[C:18](=[O:28])[c:19]3[c:20]([cH:24][cH:25][cH:26][cH:27]3)[C:21]2=[O:23])[cH:4][c:5]([O:6][Si:7]([CH3:8])([CH3:9])[C:10]([CH3:11])([CH3:12])[CH3:13])[cH:14][cH:15]1

Participants

5

Reactant 4

HCID 6228DimethylformamideHCID 6809PhthalimideHCID 5462222PotassiumHCID 19437125(4-Bromo-3-bromomethyl-phenoxy)-tert-butyl-dimethyl-silane

Product 1

HCID 179843932-[2-Bromo-5-(tert-butyl-dimethyl-silanyloxy)-benzyl]-isoindole-1,3-dione

Sources & evidence

ORD record
ord-2d89b3ad29be4c0ab5a3afa7726dc22d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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