Tetrahydrofuran → N-(5-(3-(ethylsulfonyl)phenyl)-8-methoxy-3-methyl-9H-pyrido[2,3-b]indol-7-yl)-N-methylcyclopropanecarboxamide

HRID 2315539Notes

Reaction equation

HRID 2315539 reaction equation
[CH2:1]([CH3:2])[S:3](=[O:4])(=[O:5])[c:6]1[cH:7][c:8](-[c:12]2[c:13]3[c:14]4[c:15]([nH:16][c:17]3[c:18]([O:23][CH3:24])[c:19]([NH:21][CH3:22])[cH:20]2)[n:25][cH:26][c:27]([CH3:29])[cH:28]4)[cH:9][cH:10][cH:11]1.[CH2:36]1[O:37][CH2:38][CH2:39][CH2:40]1.[CH:30]1([C:33](=[O:34])[Cl:35])[CH2:31][CH2:32]1>>[CH2:1]([CH3:2])[S:3](=[O:4])(=[O:5])[c:6]1[cH:7][c:8](-[c:12]2[c:13]3[c:14]4[c:15]([nH:16][c:17]3[c:18]([O:23][CH3:24])[c:19]([N:21]([CH3:22])[C:33]([CH:30]3[CH2:31][CH2:32]3)=[O:34])[cH:20]2)[n:25][cH:26][c:27]([CH3:29])[cH:28]4)[cH:9][cH:10][cH:11]1

Participants

4

Reactant 3

HCID 8028TetrahydrofuranHCID 77637Cyclopropanecarbonyl chlorideHCID 588801275-(3-(ethylsulfonyl)phenyl)-8-methoxy-N,3-dimethyl-9H-pyrido[2,3-b]indol-7-amine

Product 1

HCID 58880140N-(5-(3-(ethylsulfonyl)phenyl)-8-methoxy-3-methyl-9H-pyrido[2,3-b]indol-7-yl)-N-methylcyclopropanecarboxamide

Sources & evidence

ORD record
ord-408488616a7d47929b3b878dc52e167f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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