Tetrahydrofuran → 5-Bromo-3-[1-(2-chloro-phenyl)-ethoxy]-thiophene-2-carboxylic acid methyl ester
Reaction equation
[CH2:53]1[O:54][CH2:55][CH2:56][CH2:57]1.[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([Br:11])[cH:8][c:9]1[OH:10].[Cl:12][c:13]1[c:14]([CH:19]([CH3:20])[OH:21])[cH:15][cH:16][cH:17][cH:18]1.[O:41]=[C:42]([O:43][CH2:44][CH3:45])[N:46]=[N:47][C:48]([O:49][CH2:50][CH3:51])=[O:52].[c:22]1([P:23]([c:24]2[cH:25][cH:26][cH:27][cH:28][cH:29]2)[c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[cH:36][cH:37][cH:38][cH:39][cH:40]1>>[CH3:1][O:2][C:3](=[O:4])[c:5]1[s:6][c:7]([Br:11])[cH:8][c:9]1[O:10][CH:19]([c:14]1[c:13]([Cl:12])[cH:18][cH:17][cH:16][cH:15]1)[CH3:20]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-e37e96d1dccd43a88ef844266a2ebb63
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…