反应详情

A solution of 7.5 g (about 0.04 mol) of N-isopropyl-2-oxopropanesulfonamide and 6.0 g (0.04 mol) of 3-nitrobenzaldehyde in 40 ml of benzene is treated with 0.16 ml of piperidine and 0.48 ml of glacial acetic acid in an analogous manner to that described in Example 1. The oily crude product is triturated with ether, whereby crystallization occurs. There are obtained 2.5 g of α-acetyl-N-isopropyl-3-nitrostyrenesulfonamide in the form of colorless crystals, m.p. 153°-157°.

1. customThe oily crude product is triturated with ether, whereby crystallization