Tetrahydrofuran → N-(4-formyl-5-phenyl-1,3-thiazol-2-yl)acetamide

HRID 2316254Notes

Reaction equation

HRID 2316254 reaction equation
[Al+3:21].[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[s:6][c:7](-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[c:8]([C:10](=[O:11])[O:12][CH3:13])[n:9]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22]>>[C:1]([CH3:2])(=[O:3])[NH:4][c:5]1[s:6][c:7](-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[c:8]([CH:10]=[O:11])[n:9]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 21915122Methyl 2-(acetylamino)-5-phenyl-1,3-thiazole-4-carboxylate

Product 1

HCID 21915160N-(4-formyl-5-phenyl-1,3-thiazol-2-yl)acetamide

Sources & evidence

ORD record
ord-9195e61903754d72848faa567afebe1a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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