Hydrochloric Acid → (+/-)-1-(5-Chloro-7-methoxy-2,3-dihydro-1-benzofuran-2-yl)methanamine

HRID 2316263Notes

Reaction equation

HRID 2316263 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6]([O:7][CH2:8][CH:9]2[CH2:10][c:11]3[cH:12][c:13]([Cl:14])[cH:15][c:16]([O:17][CH3:18])[c:19]3[O:20]2)(=[O:21])=[O:22])[cH:23][cH:24]1.[ClH:48].[N-:26]=[N+:27]=[N-:28].[N-:45]=[N+:46]=[N-:47].[N:29](=[N+:30]=[N-:31])[CH2:32][CH:33]1[O:34][c:35]2[c:36]([cH:38][c:39]([Cl:44])[cH:40][c:41]2[O:42][CH3:43])[CH2:37]1.[Na+:25]>>[NH2:29][CH2:32][CH:33]1[O:34][c:35]2[c:36]([cH:38][c:39]([Cl:44])[cH:40][c:41]2[O:42][CH3:43])[CH2:37]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 33558Azide2×HCID 86598566(+/-)-(5-Chloro-7-methoxy-2,3-dihydro-1-benzofuran-2-yl)methyl 4-methylbenzenesulfonateHCID 86599229(+/-)-2-(Azidomethyl)-5-chloro-7-methoxy-2,3-dihydro-1-benzofuran

Product 1

HCID 68961804(+/-)-1-(5-Chloro-7-methoxy-2,3-dihydro-1-benzofuran-2-yl)methanamine

Sources & evidence

ORD record
ord-6dcf2ae21ce847d29c0b195477c12af2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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