Chloride → 6-Fluoro-2-(2-methoxyvinyl)-8-(triisopropylsilyloxy)quinoline
Reaction equation
[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:24][C:25]([CH3:26])([O-:27])[CH3:28].[CH3:2][O:3][CH2:4][P+:5]([c:6]1[cH:7][cH:8][cH:9][cH:10][cH:11]1)([c:12]1[cH:13][cH:14][cH:15][cH:16][cH:17]1)[c:18]1[cH:19][cH:20][cH:21][cH:22][cH:23]1.[Cl-:1].[F:30][c:31]1[cH:32][c:33]2[cH:34][cH:35][c:36]([CH:52]=[O:53])[n:37][c:38]2[c:39]([O:41][Si:42]([CH:43]([CH3:44])[CH3:45])([CH:46]([CH3:47])[CH3:48])[CH:49]([CH3:50])[CH3:51])[cH:40]1.[K+:29]>>[CH3:2][O:3][CH:4]=[CH:24][c:36]1[cH:35][cH:34][c:33]2[cH:32][c:31]([F:30])[cH:40][c:39]([O:41][Si:42]([CH:43]([CH3:44])[CH3:45])([CH:46]([CH3:47])[CH3:48])[CH:49]([CH3:50])[CH3:51])[c:38]2[n:37]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-eb1116b9db744e758acd8c183c6818b6
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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