Methanol → 2-Chloro-5-phenyl-6-[4-({[4-(1,2,3-thiadiazol-4-yl)benzyl]amino}methyl)phenyl]nicotinonitrile
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([Cl:23])[c:12]([C:13]#[N:14])[cH:15][c:16]2-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[cH:7][cH:8]1.[CH2:48]1[O:49][CH2:50][CH2:51][CH2:52]1.[CH3:24][OH:25].[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[s:26]1[n:27][n:28][c:29](-[c:31]2[cH:32][cH:33][c:34]([CH2:37][NH2:38])[cH:35][cH:36]2)[cH:30]1>>[CH2:2]([c:3]1[cH:4][cH:5][c:6](-[c:9]2[n:10][c:11]([Cl:23])[c:12]([C:13]#[N:14])[cH:15][c:16]2-[c:17]2[cH:18][cH:19][cH:20][cH:21][cH:22]2)[cH:7][cH:8]1)[NH:38][CH2:37][c:34]1[cH:33][cH:32][c:31](-[c:29]2[n:28][n:27][s:26][cH:30]2)[cH:36][cH:35]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-3ffc497d6539457691eb701ba5b699f1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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