Bicarbonate Ion → 2,3-dihydro-2-[2-[4-(6-Fluoro-1,2-benzisoxazol-3-yl)-1-piperidinyl]ethyl]-1H-isoindol-1-one
Reaction equation
[CH2:36]([SiH:37]([CH2:38][CH3:39])[CH2:40][CH3:41])[CH3:42].[Cl:48][CH2:49][Cl:50].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]4[CH2:18][c:19]5[cH:20][cH:21][cH:22][cH:23][c:24]5[CH:25]4[OH:26])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:27][cH:28]1.[Na+:47].[O-:43][C:44]([OH:45])=[O:46].[OH:29][C:30]([C:31]([F:32])([F:33])[F:34])=[O:35]>>[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([CH:9]3[CH2:10][CH2:11][N:12]([CH2:15][CH2:16][N:17]4[CH2:18][c:19]5[cH:20][cH:21][cH:22][cH:23][c:24]5[C:25]4=[O:26])[CH2:13][CH2:14]3)[n:7][o:8]2)[cH:27][cH:28]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fb714939fe88463daf5b1c4546d643c8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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