Tetrahydrofuran → 4-t-Butoxy-3-chloro-2,5,6-trifluoropyridine
Reaction equation
[CH2:18]1[O:19][CH2:20][CH2:21][CH2:22]1.[CH3:12][C:13]([CH3:14])([O-:15])[CH3:16].[Cl:1][c:2]1[c:3]([F:11])[n:4][c:5]([F:10])[c:6]([F:9])[c:7]1[F:8].[Li+:17]>>[Cl:1][c:2]1[c:3]([F:11])[n:4][c:5]([F:10])[c:6]([F:9])[c:7]1[O:15][C:13]([CH3:12])([CH3:14])[CH3:16]Participants
5
Sources & evidence
- ORD record
- ord-2907934dd667463eadb41b56f213d8f5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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