Acetonitrile → 9-bromo-1-chloro-N-[(1-methyl-1H-pyrazol-3-yl)methyl]benzo[c]-1,6-naphthyridin-6-amine

HRID 2317394Notes

Reaction equation

HRID 2317394 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([Cl:15])[n:7][c:8]3[cH:9][cH:10][n:11][c:12]([Cl:14])[c:13]23)[cH:16][cH:17]1.[CH3:18][n:19]1[n:20][c:21]([CH2:24][NH2:25])[cH:22][cH:23]1.[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:33][C:34]#[N:35].[CH3:36][CH2:37][O:38][C:39]([CH3:40])=[O:41]>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([c:6]([NH:25][CH2:24][c:21]3[n:20][n:19]([CH3:18])[cH:23][cH:22]3)[n:7][c:8]3[cH:9][cH:10][n:11][c:12]([Cl:14])[c:13]23)[cH:16][cH:17]1

Participants

6

Reactant 5

HCID 6342AcetonitrileHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 7019419(1-Methylpyrazol-3-yl)methanamineHCID 593754709-Bromo-1,6-dichlorobenzo[c]-1,6-naphthyridine

Product 1

HCID 593756739-bromo-1-chloro-N-[(1-methyl-1H-pyrazol-3-yl)methyl]benzo[c]-1,6-naphthyridin-6-amine

Sources & evidence

ORD record
ord-7bab19365020445bb514fa7242bf366f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

Loading…