Acetate → 1-Fluoro-4-methyl-2-phenoxybenzene

HRID 2317928Notes

Reaction equation

HRID 2317928 reaction equation
[C:40]([O-:41])(=[O:42])[CH3:43].[C:45]([O-:46])(=[O:47])[CH3:48].[CH2:49]([Cl:50])[Cl:51].[CH3:1][CH2:2][N:3]([CH2:4][CH3:5])[CH2:6][CH3:7].[Cu+2:44].[F:26][c:27]1[c:28]([O:29][CH3:30])[c:31]([F:32])[cH:33][c:34]2[c:35]1[cH:36][cH:37][n:38]2[CH3:39].[F:8][c:9]1[c:10]([OH:16])[cH:11][c:12]([CH3:15])[cH:13][cH:14]1.[OH:17][B:18]([OH:19])[c:20]1[cH:21][cH:22][cH:23][cH:24][cH:25]1>>[F:8][c:9]1[c:10]([O:16][c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:11][c:12]([CH3:15])[cH:13][cH:14]1

Participants

8

Reactant 7

HCID 175Acetate2×HCID 6344DichloromethaneHCID 8471TriethylamineHCID 27099Cupric cationHCID 66827Phenylboronic AcidHCID 182387Phenol, 2-fluoro-5-methyl-HCID 210715554,6-Difluoro-5-methoxy-1-methyl-1H-indole

Product 1

HCID 142572981-Fluoro-4-methyl-2-phenoxybenzene

Sources & evidence

ORD record
ord-1de7d2ee55ef4edaa9a56aa0b8fb7ef6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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