2-Aminothiazole → 3-cyclopentyl-2-[3-methylsulfonyl-4-(5-methyltetrazol-1-yl)phenyl]-N-(1,3-thiazol-2-yl)prop-2-enamide
Reaction equation
[Br:20][N:21]1[C:22](=[O:23])[CH2:24][CH2:25][C:26]1=[O:27].[CH2:60]([Cl:61])[Cl:62].[CH:28]1([CH:33]=[C:34]([C:35](=[O:36])[OH:37])[c:38]2[cH:39][c:40]([S:50](=[O:51])(=[O:52])[CH3:53])[c:41](-[n:44]3[n:45][n:46][n:47][c:48]3[CH3:49])[cH:42][cH:43]2)[CH2:29][CH2:30][CH2:31][CH2:32]1.[NH2:54][c:55]1[s:56][cH:57][cH:58][n:59]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH:28]1([CH:33]=[C:34]([C:35](=[O:37])[NH:54][c:55]2[s:56][cH:57][cH:58][n:59]2)[c:38]2[cH:39][c:40]([S:50](=[O:51])(=[O:52])[CH3:53])[c:41](-[n:44]3[n:45][n:46][n:47][c:48]3[CH3:49])[cH:42][cH:43]2)[CH2:29][CH2:30][CH2:31][CH2:32]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4d008b570e7648559a88f6a3035bd14b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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