Potassium Cation → tert-butyl 4-(5-cyclopropyl-3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate

HRID 2318746Notes

Reaction equation

HRID 2318746 reaction equation
[C:37](=[O:38])([O-:39])[O-:40].[CH3:43][CH2:44][O:45][C:46]([CH3:47])=[O:48].[CH:11]1([c:14]2[c:15]([N:24]3[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]3)[c:16]3[c:17]([n:18][cH:19]2)[nH:20][n:21][c:22]3[I:23])[CH2:12][CH2:13]1.[Cl:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([O:9][CH3:10])[cH:7][cH:8]1.[K+:41].[K+:42].[O:49]=[CH:50][N:51]([CH3:52])[CH3:53].[OH2:54]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([O:9][CH3:10])[cH:7][cH:8]1)[n:20]1[c:17]2[c:16]([c:15]([N:24]3[CH2:25][CH2:26][N:27]([C:30](=[O:31])[O:32][C:33]([CH3:34])([CH3:35])[CH3:36])[CH2:28][CH2:29]3)[c:14]([CH:11]3[CH2:12][CH2:13]3)[cH:19][n:18]2)[c:22]([I:23])[n:21]1

Participants

8

Reactant 7

HCID 813Potassium Cation2×HCID 962WaterHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 19660Carbonate IonHCID 699934-Methyloxybenzyl chlorideHCID 178452207HCID 178452207, compound

Product 1

HCID 68761344tert-butyl 4-(5-cyclopropyl-3-iodo-1-(4-methoxybenzyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)piperazine-1-carboxylate

Sources & evidence

ORD record
ord-4259405471654d95a63956b3e4c031c0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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