Chloride → Diethyl [2-(2-Fluorophenyl)-2-oxoethyl]phosphonate

HRID 2319484Notes

Reaction equation

HRID 2319484 reaction equation
[CH2:1]([CH3:2])[O:3][P:4](=[O:5])([O:6][CH2:7][CH3:8])[CH2:9][C:10](=[O:11])[OH:12].[CH3:13][CH2:14][N:15]([CH2:16][CH3:17])[CH2:18][CH3:19].[CH3:38][c:39]1[cH:40][cH:41][cH:42][cH:43][cH:44]1.[Cl-:25].[Cl-:27].[Cl:20][Si:21]([CH3:22])([CH3:23])[CH3:24].[F:28][c:29]1[c:30]([C:31]([Cl:32])=[O:33])[cH:34][cH:35][cH:36][cH:37]1.[Mg+2:26]>>[CH2:1]([CH3:2])[O:3][P:4](=[O:5])([O:6][CH2:7][CH3:8])[CH2:9][C:10](=[O:12])[c:30]1[c:29]([F:28])[cH:37][cH:36][cH:35][cH:34]1

Participants

8

Reactant 7

HCID 312Chloride2×HCID 888Magnesium CationHCID 1140TolueneHCID 6397ChlorotrimethylsilaneHCID 8471TriethylamineHCID 98082-Fluorobenzoyl chlorideHCID 36704(Diethoxyphosphinyl)acetic acid

Product 1

HCID 86585808Diethyl [2-(2-Fluorophenyl)-2-oxoethyl]phosphonate

Sources & evidence

ORD record
ord-28ff8c70ec5a4895a236f05f726be598
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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