Hydrochloric Acid → 6-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazole-5-carboxylic acid

HRID 2319722Notes

Reaction equation

HRID 2319722 reaction equation
[CH3:1][O:2][C:3](=[O:4])[c:5]1[cH:6][c:7]2[c:8]([n:9][cH:10][nH:11]2)[c:12]([F:23])[c:13]1[NH:14][c:15]1[c:16]([Cl:22])[cH:17][c:18]([Br:21])[cH:19][cH:20]1.[CH3:26][CH2:27][OH:28].[CH3:29][CH2:30][O:31][C:32](=[O:33])[CH3:34].[ClH:36].[Na+:25].[OH-:24].[OH2:35]>>[O:2]=[C:3]([OH:4])[c:5]1[cH:6][c:7]2[c:8]([n:9][cH:10][nH:11]2)[c:12]([F:23])[c:13]1[NH:14][c:15]1[c:16]([Cl:22])[cH:17][c:18]([Br:21])[cH:19][cH:20]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 702EthanolHCID 923Sodium ionHCID 961HydroxideHCID 962WaterHCID 8857Ethyl AcetateHCID 11749905Methyl 6-((4-bromo-2-chlorophenyl)amino)-7-fluoro-1H-benzo[d]imidazole-5-carboxylate

Product 1

HCID 211141586-(4-Bromo-2-chloro-phenylamino)-7-fluoro-3H-benzoimidazole-5-carboxylic acid

Sources & evidence

ORD record
ord-3adcbb5e15f040f3af0c8442c3d939e3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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