Chloride → 4-Acetyl-piperidine-1-carboxylic acid tert-butyl ester

HRID 2319894Notes

Reaction equation

HRID 2319894 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[N:16]([O:17][CH3:18])[CH3:19])[CH2:12][CH2:13]1.[CH3:26][Mg+:27].[Cl-:25].[O:20]1[CH2:21][CH2:24][CH2:23][CH2:22]1.[O:28]1[CH2:29][CH2:30][CH2:31][CH2:32]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[CH3:21])[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028Tetrahydrofuran2×HCID 11065582tert-Butyl 4-(methoxy(methyl)carbamoyl)piperidine-1-carboxylateHCID 178477777HCID 178477777, compound

Product 1

HCID 109879834-Acetyl-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-4dfc8ed4131e4506b16c5d46ae05f020
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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