Hydrochloric Acid → Benzoyl fluoride, 2,3,4-trichloro-5-fluoro-

HRID 231993Notes

Reaction equation

HRID 231993 reaction equation
[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]([Cl:12])[C:8]([F:13])=[CH:7][C:3]=1[C:4](Cl)=[O:5].[FH:14].Cl>>[Cl:1][C:2]1[C:10]([Cl:11])=[C:9]([Cl:12])[C:8]([F:13])=[CH:7][C:3]=1[C:4]([F:14])=[O:5]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 14917Hydrofluoric AcidHCID 141498692,3,4-Trichloro-5-fluorobenzoyl chloride

Product 1

HCID 14149871Benzoyl fluoride, 2,3,4-trichloro-5-fluoro-

Procedure

480 g (1.83 mols) of 2,3,4-trichloro-5-fluorobenzoyl chloride are introduced, with 240 g (12 mols) of hydrogen fluoride, at -5° to 0° C. into a stirred autoclave fitted with a pressure-control valve, the apparatus is pressure-sealed and warmed to 70° C. in steps, corresponding to the evolution of HCl. The hydrogen chloride produced is continuously released at 4-5 bar. When the evolution of HCl is complete, the mixture is cooled, the excess pressure is released and the reaction mixture is fractionated.

Workup

  1. customfitted with a pressure-control valve
  2. customthe apparatus is pressure-sealed

Sources & evidence

ORD record
ord-21bf16f3a7db4138a26664dbdd4061e5
Source dataset
uspto-grants-1989_07
Patent number
US04851160

Reaction notes

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