Acetate → 3-{4-[4-(4-Methylbenzoyl)piperidine-1-carbonyl]phenyl}oxazolidin-2-one

HRID 2320001Notes

Reaction equation

HRID 2320001 reaction equation
[CH3:30][B:31]([OH:32])[OH:33].[CH:34]1([P:35]([CH:36]2[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]2)[c:42]2[cH:43][cH:44][cH:45][cH:46][c:47]2-[c:48]2[c:49]([O:50][CH3:51])[cH:52][cH:53][cH:54][c:55]2[O:56][CH3:57])[CH2:58][CH2:59][CH2:60][CH2:61][CH2:62]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:6](=[O:7])[CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[c:16]3[cH:17][cH:18][c:19]([N:22]4[C:23](=[O:27])[O:24][CH2:25][CH2:26]4)[cH:20][cH:21]3)[CH2:12][CH2:13]2)[cH:28][cH:29]1.[F-:63].[K+:64].[O-:66][C:67]([CH3:68])=[O:69].[O-:70][C:71]([CH3:72])=[O:73].[O:75]1[CH2:76][CH2:77][CH2:78][CH2:79]1.[OH2:74].[Pd+2:65]>>[c:2]1([CH3:30])[cH:3][cH:4][c:5]([C:6](=[O:7])[CH:8]2[CH2:9][CH2:10][N:11]([C:14](=[O:15])[c:16]3[cH:17][cH:18][c:19]([N:22]4[C:23](=[O:27])[O:24][CH2:25][CH2:26]4)[cH:20][cH:21]3)[CH2:12][CH2:13]2)[cH:28][cH:29]1

Participants

10

Reactant 9

HCID 175Acetate2×HCID 813Potassium CationHCID 962WaterHCID 8028TetrahydrofuranHCID 28179Fluoride IonHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 139377Methylboronic AcidHCID 112698722-Dicyclohexylphosphino-2',6'-dimethoxybiphenylHCID 673809143-{4-[4-(4-Chlorobenzoyl)piperidine-1-carbonyl]phenyl}oxazolidin-2-one

Product 1

HCID 673808473-{4-[4-(4-Methylbenzoyl)piperidine-1-carbonyl]phenyl}oxazolidin-2-one

Sources & evidence

ORD record
ord-db51ed8afd9e48d6a6844a9a47185ca6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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