Tetrahydrofuran → 3-(2-Fluorobenzyl)-7-(2-thiazolyl)-3H-[1,2,3]triazolo[4,5-d]pyrimidine-5-amine
Reaction equation
[CH2:30]1[O:31][CH2:32][CH2:33][CH2:34]1.[CH3:6][CH2:7][CH2:8][CH2:9][Li:10].[Cl:11][c:12]1[c:13]2[c:14]([n:15][c:16]([NH2:18])[n:17]1)[n:19]([CH2:22][c:23]1[c:24]([F:29])[cH:25][cH:26][cH:27][cH:28]1)[n:20][n:21]2.[cH:1]1[cH:2][s:3][cH:4][n:5]1.[cH:35]1[cH:36][cH:37][c:38]([P:39]([Pd:40]([P:41]([c:42]2[cH:43][cH:44][cH:45][cH:46][cH:47]2)([c:48]2[cH:49][cH:50][cH:51][cH:52][cH:53]2)[c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)([P:60]([c:61]2[cH:62][cH:63][cH:64][cH:65][cH:66]2)([c:67]2[cH:68][cH:69][cH:70][cH:71][cH:72]2)[c:73]2[cH:74][cH:75][cH:76][cH:77][cH:78]2)[P:79]([c:80]2[cH:81][cH:82][cH:83][cH:84][cH:85]2)([c:86]2[cH:87][cH:88][cH:89][cH:90][cH:91]2)[c:92]2[cH:93][cH:94][cH:95][cH:96][cH:97]2)([c:98]2[cH:99][cH:100][cH:101][cH:102][cH:103]2)[c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[cH:110][cH:111]1>>[cH:1]1[cH:2][s:3][c:4](-[c:12]2[c:13]3[c:14]([n:15][c:16]([NH2:18])[n:17]2)[n:19]([CH2:22][c:23]2[c:24]([F:29])[cH:25][cH:26][cH:27][cH:28]2)[n:20][n:21]3)[n:5]1Participants
6
Sources & evidence
- ORD record
- ord-1f9a88c10a584b9099a1cb160aaa49da
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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