Potassium Cation → 3-[2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo [1,2-b]pyrazol-3-yl)-pyrazolo[1,5-a]pyrimidine

HRID 2320912Notes

Reaction equation

HRID 2320912 reaction equation
[Br:1][c:2]1[cH:3][n:4][n:5]2[c:6]1[n:7][cH:8][cH:9][cH:10]2.[C:47](=[O:48])([O-:49])[O-:50].[CH3:53][CH2:54][O:55][C:56](=[O:57])[CH3:58].[K+:51].[K+:52].[O:115]1[CH2:116][CH2:117][O:118][CH2:119][CH2:120]1.[O:61]=[C:62]([CH:63]=[CH:64][c:65]1[cH:66][cH:67][cH:68][cH:69][cH:70]1)[CH:71]=[CH:72][c:73]1[cH:74][cH:75][cH:76][cH:77][cH:78]1.[O:79]=[C:80]([CH:81]=[CH:82][c:83]1[cH:84][cH:85][cH:86][cH:87][cH:88]1)[CH:89]=[CH:90][c:91]1[cH:92][cH:93][cH:94][cH:95][cH:96]1.[O:97]=[C:98]([CH:99]=[CH:100][c:101]1[cH:102][cH:103][cH:104][cH:105][cH:106]1)[CH:107]=[CH:108][c:109]1[cH:110][cH:111][cH:112][cH:113][cH:114]1.[Pd:59].[Pd:60].[c:28]1([P:29]([c:30]2[cH:31][cH:32][cH:33][cH:34][cH:35]2)[c:36]2[cH:37][cH:38][cH:39][cH:40][cH:41]2)[cH:42][cH:43][cH:44][cH:45][cH:46]1.[n:11]1[c:12](-[c:17]2[c:18]([B:25]([OH:26])[OH:27])[c:19]3[n:20]([n:21]2)[CH2:22][CH2:23][CH2:24]3)[cH:13][cH:14][cH:15][cH:16]1>>[c:2]1(-[c:18]2[c:17](-[c:12]3[n:11][cH:16][cH:15][cH:14][cH:13]3)[n:21][n:20]3[c:19]2[CH2:24][CH2:23][CH2:22]3)[cH:3][n:4][n:5]2[c:6]1[n:7][cH:8][cH:9][cH:10]2

Participants

10

Reactant 9

HCID 813Potassium Cation2×HCID 8857Ethyl AcetateHCID 11776TriphenylphosphineHCID 19660Carbonate IonHCID 23938Palladium2×HCID 312751,4-DioxaneHCID 95417Dibenzylidene acetone3×HCID 122032083-Bromopyrazolo(1,5-a)pyrimidineHCID 59710031(2-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole-3-boronic acid

Product 1

HCID 104249963-[2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo [1,2-b]pyrazol-3-yl)-pyrazolo[1,5-a]pyrimidine

Sources & evidence

ORD record
ord-947ad1f98fc2421e84cdeb2497933a89
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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