Hydrochloric Acid → N-(6-bromopyridin-3-yl)-2-[2,5-dimethyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide

HRID 2321019Notes

Reaction equation

HRID 2321019 reaction equation
[Br:20][CH2:21][C:22](=[O:23])[NH:24][c:25]1[cH:26][n:27][c:28]([Br:31])[cH:29][cH:30]1.[CH3:2][CH:3]1[N:4]([c:10]2[n:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)[CH2:5][CH:6]([CH3:9])[NH:7][CH2:8]1.[ClH:1].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[CH3:2][CH:3]1[N:4]([c:10]2[n:11][cH:12][c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][cH:15]2)[CH2:5][CH:6]([CH3:9])[N:7]([CH2:21][C:22](=[O:23])[NH:24][c:25]2[cH:26][n:27][c:28]([Br:31])[cH:29][cH:30]2)[CH2:8]1

Participants

5

Reactant 4

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 4203084Piperazine, 2,5-dimethyl-1-[5-(trifluoromethyl)-2-pyridinyl]-HCID 771748692-bromo-N-(6-bromo-3-pyridinyl)acetamide

Product 1

HCID 86635129N-(6-bromopyridin-3-yl)-2-[2,5-dimethyl-4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]acetamide

Sources & evidence

ORD record
ord-54cfc64aecb04d1d8eb1080927d33e16
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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